Who should consider ASST?
Anyone with chronic urticaria (hives or wheals lasting more than 6 weeks) that responds poorly to standard antihistamines, or who has a family history of autoimmune disease.
How the test is performed
A small amount of your own serum is separated from a routine blood draw and injected intradermally on the forearm. A control of saline is injected alongside. Wheal and flare reactions are measured at 30 minutes.
What a positive result means
A positive ASST suggests autoantibodies are activating mast cells. Your urticaria is likely autoimmune and may benefit from omalizumab, cyclosporine or other targeted therapy — beyond plain antihistamines.
Combined with allergy and bloodwork
We typically order ASST alongside a thyroid panel, ANA, total IgE, CBC and a food allergy review at our Gachibowli clinic — building a complete picture in one workup.